MAPK7 Antikörper (Mitogen-Activated Protein Kinase 7)

Details for Product anti-MAPK7 Antibody No. ABIN6569113
Target
Reaktivität
Human, Maus
150
110
105
3
2
2
2
2
2
1
Wirt
Kaninchen
142
4
3
2
Klonalität
Polyklonal
Konjugat
Dieser MAPK7 Antikörper ist unkonjugiert
11
8
8
8
7
6
6
6
6
5
5
5
5
5
2
2
2
Applikation
Immunofluorescence (IF), Western Blotting (WB)
75
66
34
33
19
6
5
4
2
2
2
1
1
Optionen
Immunogen Recombinant protein of human MAPK7
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ERK 5 (MAPK7 Antibody Abstract)
Hintergrund

Synonyms: Big MAP kinase 1,BMK 1,BMK 1 kinase,BMK-1,BMK1,BMK1 Kinase,EC 2.7.11.24,ERK 4,ERK 5,ERK-5,ERK4,ERK5,Extracellular signal regulated kinase 5,Extracellular signal-regulated kinase 5,MAP kinase 7,MAPK 7,MAPK7,Mitogen activated protein kinase 7,Mitogen-activated protein kinase 7,MK07,OTTHUMP00000065906,OTTHUMP00000065907,PRKM 7,PRKM7,PROTEIN KINASE,MITOGEN-ACTIVATED,7

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Molekulargewicht

Observed_MW: 47kDa

Calculated_MW: 50kDa/59kDa/73kDa/88kDa

Gen-ID 5598
UniProt Q13164
Pathways MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Mitogen-Activated Protein Kinase 7 (MAPK7) antibody (ABIN6569113) Immunofluorescence analysis of MCF-7 cells using MAPK7 antibody.
Image no. 2 for anti-Mitogen-Activated Protein Kinase 7 (MAPK7) antibody (ABIN6569113) Western blot analysis of extracts of various cell lines, using MAPK7 antibody.