RAD9A Antikörper (RAD9 Homolog A (S. Pombe))

Details for Product anti-RAD9A Antibody No. ABIN6568964
Target
Reaktivität
Human, Maus, Ratte
222
78
68
6
4
2
2
1
1
Wirt
Kaninchen
256
11
7
Klonalität
Polyklonal
Konjugat
Dieser RAD9A Antikörper ist unkonjugiert
21
21
19
12
12
12
10
9
9
9
9
9
8
8
8
8
8
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
161
105
101
73
41
18
10
10
10
9
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human RAD9A
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RAD9A (RAD9A Antibody Abstract)
Hintergrund

Synonyms: Cell cycle checkpoint control protein,Cell cycle checkpoint control protein RAD9A,DNA repair exonuclease rad9 homolog A,hRAD 9,hRAD9,Rad 9,RAD 9A,RAD9 (S pombe) homolog,RAD9 homolog A,RAD9 homolog,Rad9a,RAD9A

Background: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 27kDa

Calculated_MW: 42kDa

Gen-ID 5883
UniProt Q99638
Pathways Positive Regulation of Response to DNA Damage Stimulus
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibody (ABIN6568964) Western blot analysis of extracts of mouse testis, using RAD9A antibody.
Image no. 2 for anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibody (ABIN6568964) Immunohistochemistry of paraffin-embedded human liver injury using RAD9A antibody.
Image no. 3 for anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibody (ABIN6568964) Immunofluorescence analysis of MCF-7 cells using RAD9A antibody.
Image no. 4 for anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibody (ABIN6568964) Immunohistochemistry of paraffin-embedded rat liver using RAD9A antibody.