RAD9A Antikörper (AA 162-391)
Kurzübersicht für RAD9A Antikörper (AA 162-391) (ABIN3022652)
Target
Alle RAD9A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 162-391
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Sequenz
- ALAEVTLGIG RGRRVILRSY HEEEADSTAK AMVTEMCLGE EDFQQLQAQE GVAITFCLKE FRGLLSFAES ANLNLSIHFD APGRPAIFTI KDSLLDGHFV LATLSDTDSH SQDLGSPERH QPVPQLQAHS TPHPDDFAND DIDSYMIAME TTIGNEGSRV LPSISLSPGP QPPKSPGPHS EEEDEAEPST VPGTPPPKKF RSLFFGSILA PVRSPQGPSP VLAEDSEGEG
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Andere Bezeichnung
- RAD9A
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Hintergrund
- This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RAD9A,RAD9,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,RAD9A
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Molekulargewicht
- 42 kDa
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Gen-ID
- 5883
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UniProt
- Q99638
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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