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RAD9A Produkte

(RAD9 Homolog A (S. Pombe) (RAD9A))

Kategorien

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Ausgewählte RAD9A Kategorien

RAD9A Antikörper

High quality antibodies with extensive validation data.

RAD9A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RAD9A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (6)
Kat. Nr. ABIN3022652
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p), IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN2857053
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), DB
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN389633
Menge 400 μL
Datenblatt Datenblatt

Empfohlene RAD9A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6206964
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RAD9A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317298
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3137560
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094931
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RAD9A Produkten

Awate, De Benedetti: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." in: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).

Yun, Shi, Yang, Zhang, Wang, Zhou, Mu: "Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy." in: Scientific reports, Vol. 4, pp. 7548, (2015) (PubMed).

Kelly, Davey: "Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit." in: PLoS ONE, Vol. 8, Issue 12, pp. e85859, (2013) (PubMed).

Ronald, Awate, Rath, Carroll, Galiano, Dwyer, Kleiner-Hancock, Mathis, Vigod, De Benedetti: "Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy." in: Genes & cancer, Vol. 4, Issue 1-2, pp. 39-53, (2013) (PubMed).

Warmerdam, Brinkman, Marteijn, Medema, Kanaar, Smits: "UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway." in: Journal of cell science, Vol. 126, Issue Pt 9, pp. 1923-30, (2013) (PubMed).

Mohni, Dee, Smith, Schumacher, Weller: "Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins." in: Journal of virology, Vol. 87, Issue 1, pp. 531-42, (2012) (PubMed).

Bai, Madabushi, Guan, Lu: "Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1." in: DNA repair, Vol. 9, Issue 5, pp. 478-87, (2010) (PubMed).

De Haro, Wray, Williamson, Durant, Corwin, Gentry, Osheroff, Lee, Hromas, Nickoloff: "Metnase promotes restart and repair of stalled and collapsed replication forks." in: Nucleic acids research, Vol. 38, Issue 17, pp. 5681-91, (2010) (PubMed).

Ha, Lee, Palii, Brown, Takeda, Liu, Bhalla, Robertson: "Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery." in: Human molecular genetics, Vol. 20, Issue 1, pp. 126-40, (2010) (PubMed).

Medhurst, Warmerdam, Akerman, Verwayen, Kanaar, Smits, Lakin: "ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage." in: Journal of cell science, Vol. 121, Issue Pt 23, pp. 3933-40, (2008) (PubMed).

Synonyme und alternative Namen zu RAD9A

RAD9 checkpoint clamp component A (RAD9A), RAD9 checkpoint clamp component A (Rad9a), RAD9 checkpoint clamp component A (rad9a), RAD9 checkpoint clamp component B (rad9b), RAD9 checkpoint clamp component A L homeolog (rad9a.L), MGC89062, RAD9, Rad9, rad9, rad9a, XRad9

Bezeichner auf Proteinebene für RAD9A

  • DNA repair exonuclease rad9 homolog A
  • cell cycle checkpoint control protein RAD9A
  • hRAD9
  • RAD9 homolog A (S. pombe)
  • cell cycle checkpoint control protein RAD9A-like
  • Rad9-like protein
  • mRAD9
  • RAD9 homolog A
  • rCG47324-like
  • PCNA-like DNA checkpoint protein Rad9
  • RAD9 checkpoint clamp component A L homeolog
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