CHRNA4 Antikörper

Produktnummer ABIN6568827

Produktdetails anti-CHRNA4 Antikörper

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CHRNA4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4 (CHRNA4 Produkte)

Synonyme: NACHRA4 antikoerper, BFNC antikoerper, EBN antikoerper, EBN1 antikoerper, NACHR antikoerper, NACRA4 antikoerper, NARAC antikoerper, Acra-4 antikoerper, Acra4 antikoerper, ENFL1 antikoerper, neuronal acetylcholine receptor subunit alpha-4 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, cholinergic receptor nicotinic alpha 4 subunit antikoerper, cholinergic receptor, nicotinic, alpha 4b antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 4 antikoerper, CpipJ_CPIJ002434 antikoerper, LOC100368057 antikoerper, CHRNA4 antikoerper, chrna4b antikoerper, Chrna4 antikoerper

Hintergrund: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 75kDa

Calculated_MW: 60kDa/69kDa

Gen-ID: 1137

UniProt: P43681

Pathways: Synaptic Membrane