Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) Antikörper

Details zu Produkt Nr. ABIN6568827
Target
Reaktivität
Maus
38
15
10
4
3
3
2
2
1
1
1
1
Wirt
Kaninchen
23
14
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Western Blotting (WB)
33
23
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human CHRNA4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CHRNA4 (CHRNA4 Antibody Abstract)
Hintergrund

Synonyms: A4 nicotinic receptor,Acetylcholine receptor alpha 4 neural,Acetylcholine receptor neuronal nicotinic alpha 4 subunit,ACH 4,ACH4,ACHA4,AChR,Acra 4,Acra4,Alpha4 nAChR,BFNC,Cholinergic receptor nicotinic alpha 4,Cholinergic receptor nicotinic alpha polypeptide 4,CHRNA 4,CHRNA4,EBN 1,EBN,EBN1,NACHR,NACRA 4,NACRA4,Neuronal acetylcholine receptor subunit alpha-4,Neuronal nicotinic acetylcholine receptor alpha 4 subunit

Background: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 75kDa

Calculated_MW: 60kDa/69kDa

Gen-ID 1137
UniProt P43681
Pathways Synaptic Membrane
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibody (ABIN6568827) Western blot analysis of extracts of mouse kidney, using CHRNA4 antibody.