BRISC and BRCA1-A Complex Member 2 (BABAM2) Antikörper

Details zu Produkt Nr. ABIN6568579
Target
Reaktivität
Human, Maus, Ratte
4
Wirt
Kaninchen
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
Applikation
Western Blotting (WB)
4
1
1
Optionen
Immunogen Recombinant protein of human BRE
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung BABAM2
Hintergrund

Synonyms: 6030405P19Rik,AI429776,B830038C02Rik,Brain and reproductive organ expressed (TNFRSF1A modulator),brain and reproductive organ expressed protein,Brain and reproductive organ-expressed protein,BRCA1 A complex subunit BRE,BRCA1-A complex subunit BRE,BRCA1/BRCA2 containing complex subunit 4,BRCA1/BRCA2 containing complex subunit 45,BRCA1/BRCA2-containing complex subunit 45,BRCC4,BRCC45,bre,BRE

Background: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

Molekulargewicht

Observed_MW: 44kDa

Calculated_MW: 42kDa/43kDa/46kDa

Gen-ID 9577
UniProt Q9NXR7
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-BRISC and BRCA1-A Complex Member 2 (BABAM2) antibody (ABIN6568579) Western blot analysis of extracts of various cell lines, using BRE antibody.