MTRR Antikörper (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase)

Details for Product anti-MTRR Antibody No. ABIN6568413
Target
Reaktivität
Human
13
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
10
3
Klonalität
Polyklonal
Konjugat
Dieser MTRR Antikörper ist unkonjugiert
1
1
1
Applikation
Western Blotting (WB)
10
7
3
Optionen
Immunogen Recombinant protein of human MTRR
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung MTRR (MTRR Antibody Abstract)
Hintergrund

Synonyms: [methionine synthase] cobalamin methyltransferase (cob(II)alamin reducing) ,5 methyltetrahydrofolate homocysteine methyltransferase reductase,cblE,Methionine synthase reductase,Methionine synthase reductase, mitochondrial,MGC129643,MSR

Background: This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht

Observed_MW: 80kDa

Calculated_MW: 6kDa/77kDa/80kDa

Gen-ID 4552
UniProt Q9UBK8
Pathways Methionine Biosynthetic Process
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) antibody (ABIN6568413) Western blot analysis of extracts of various cell lines, using MTRR antibody.