PRAME Antikörper (Preferentially Expressed Antigen in Melanoma)

Details for Product anti-PRAME Antibody No. ABIN6568373
Target
Reaktivität
Human, Maus, Ratte
58
4
4
3
3
2
2
2
1
Wirt
Kaninchen
56
2
Klonalität
Polyklonal
Konjugat
Dieser PRAME Antikörper ist unkonjugiert
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
35
13
10
9
7
5
5
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human PRAME
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PRAME (PRAME Antibody Abstract)
Hintergrund

Synonyms: 4930534P07Rik,Cancer/testis antigen 130,CT130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,Opa interacting protein OIP4,OPA-interacting protein 4,PRAME,PRAME,Preferentially expressed antigen in melanoma ,Preferentially expressed antigen of melanoma,RP23-250F8.3

Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 58kDa

Calculated_MW: 57kDa

Gen-ID 23532
UniProt P78395
Pathways Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Preferentially Expressed Antigen in Melanoma (PRAME) antibody (ABIN6568373) Western blot analysis of extracts of various cell lines, using PRAME antibody.