PRAME Antikörper (AA 1-200)
Kurzübersicht für PRAME Antikörper (AA 1-200) (ABIN7269507)
Target
Alle PRAME Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-200
-
Verwendungszweck
- PRAME Rabbit pAb
-
Sequenz
- MERRRLWGSI QSRYISMSVW TSPRRLVELA GQSLLKDEAL AIAALELLPR ELFPPLFMAA FDGRHSQTLK AMVQAWPFTC LPLGVLMKGQ HLHLETFKAV LDGLDVLLAQ EVRPRRWKLQ VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRAME (NP_006106.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
-
Andere Bezeichnung
- PRAME
-
Hintergrund
- This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.,PRAME,CT130,MAPE,OIP-4,OIP4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor biomarkers,PRAME
-
Molekulargewicht
- 57kDa
-
Gen-ID
- 23532
-
UniProt
- P78395
-
Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
Target
-