PRAME Antikörper
Kurzübersicht für PRAME Antikörper (ABIN6568373)
Target
Alle PRAME Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human PRAME
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
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Andere Bezeichnung
- PRAME
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Hintergrund
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Synonyms: 4930534P07Rik,Cancer/testis antigen 130,CT130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,Opa interacting protein OIP4,OPA-interacting protein 4,PRAME,PRAME,Preferentially expressed antigen in melanoma ,Preferentially expressed antigen of melanoma,RP23-250F8.3
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
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Observed_MW: 58kDa
Calculated_MW: 57kDa
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Gen-ID
- 23532
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UniProt
- P78395
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
Target
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