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MICA Antikörper

MICA Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6568196
  • Target Alle MICA Antikörper anzeigen
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Reaktivität
    • 70
    • 18
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 37
    • 33
    Kaninchen
    Klonalität
    • 37
    • 34
    Polyklonal
    Konjugat
    • 45
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MICA Antikörper ist unkonjugiert
    Applikation
    • 45
    • 37
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MICA (NP_000238.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MICA Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Andere Bezeichnung
    MICA (MICA Produkte)
    Synonyme
    MIC-A antikoerper, PERB11.1 antikoerper, MHC class I polypeptide-related sequence A antikoerper, MICA antikoerper
    Hintergrund
    This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
    Molekulargewicht

    Observed_MW: 43kDa

    Calculated_MW: 31kDa/42kDa

    Gen-ID
    100507436
    UniProt
    Q29983
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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