RIN2 Antikörper (Ras and Rab Interactor 2)

Details for Product anti-RIN2 Antibody No. ABIN6568165
Target
Reaktivität
Human, Maus
10
3
2
2
2
2
1
Wirt
Kaninchen
5
5
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
10
7
1
1
Optionen
Immunogen Recombinant protein of human RIN2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RIN2 (RIN2 Antibody Abstract)
Hintergrund

Synonyms: MACS ,RAB5 interacting protein 2,Ras and Rab interactor 2,RAS association (RalGDS/AF-6) domain containing protein JC265,Ras association domain family 4,Ras inhibitor JC265,Ras interaction/interference protein 2,RASSF4,RIN 2,RIN2,RIN2

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 120kDa

Calculated_MW: 100kDa/105kDa

Gen-ID 54453
UniProt Q8WYP3
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Ras and Rab Interactor 2 (RIN2) antibody (ABIN6568165) Western blot analysis of extracts of various cell lines, using RIN2 antibody.