Diazepam Binding Inhibitor Antikörper

Produktnummer ABIN6567860

Dieses Anti-Diazepam Binding Inhibitor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Diazepam Binding Inhibitor in IHC und IF. Geeignet für Human und Maus.

Kurzübersicht für Diazepam Binding Inhibitor Antikörper (ABIN6567860)

Target: Diazepam Binding Inhibitor (DBI)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Diazepam Binding Inhibitor Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DBI (NP_001171513.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Diazepam Binding Inhibitor

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: DBI

Hintergrund: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht:

Observed_MW: 11kDa

Calculated_MW: 10kDa/11kDa/13kDa/14kDa/16kDa

Gen-ID: 1622

UniProt: P07108