NLRC4 Antikörper

Produktnummer ABIN6567785

Produktdetails anti-NLRC4 Antikörper

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRC4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of mouse NLRC4 (NP_001028539.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Andere Bezeichnung: NLRC4 (NLRC4 Produkte)

Synonyme: CARD12 antikoerper, CLAN antikoerper, CLAN1 antikoerper, CLANA antikoerper, CLANB antikoerper, CLANC antikoerper, CLAND antikoerper, CLR2.1 antikoerper, IPAF antikoerper, 9530011P19Rik antikoerper, Card12 antikoerper, NLR family CARD domain containing 4 antikoerper, NLR family, CARD domain containing 4 antikoerper, NLRC4 antikoerper, Nlrc4 antikoerper

Hintergrund: This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 116kDa

Calculated_MW: 116kDa

Gen-ID: 268973

UniProt: Q3UP24

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome