SLC12A1 Antikörper (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1)

Details for Product anti-SLC12A1 Antibody No. ABIN6567726
Target
Reaktivität
Human, Maus, Ratte
55
43
39
6
4
4
3
2
2
2
1
Wirt
Kaninchen
53
4
2
Klonalität
Polyklonal
Konjugat
Dieser SLC12A1 Antikörper ist unkonjugiert
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
52
38
13
9
5
4
3
3
3
1
Optionen
Immunogen A synthetic peptide of human SLC12A1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SLC12A1 (SLC12A1 Antibody Abstract)
Hintergrund

Synonyms: BSC1,Bumetanide sensitive sodium 3,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2,Kidney specific Na K Cl symporter,Kidney-specific Na-K-Cl symporter,MGC48843,Na K 2Cl cotransporter,NKCC2,potassiumchloride cotransporter 2,S12A1,Slc12a1,sodium potassium chloride cotransporter 2,solute carrier family 12 (sodium/potassium/chloride transporters),Solute carrier family 12 member 1

Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

Molekulargewicht

Observed_MW: 150kDa

Calculated_MW: 121kDa

Gen-ID 6557
UniProt Q13621
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibody (ABIN6567726) Western blot analysis of extracts of various cell lines, using SLC12A1 antibody.