SLC12A1 Antikörper

Produktnummer ABIN7131078

Produktdetails anti-SLC12A1 Antikörper

Target: SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC12A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human SLC12A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC12A1

Target: SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))

Andere Bezeichnung: SLC12A1 (SLC12A1 Produkte)

Synonyme: slc12a1 antikoerper, SLC12A1 antikoerper, DKFZp469A2020 antikoerper, BSC1 antikoerper, NKCC2 antikoerper, Nkcc2 antikoerper, AI788571 antikoerper, D630042G03Rik antikoerper, mBSC1 antikoerper, urehr3 antikoerper, si:ch211-220f12.1 antikoerper, solute carrier family 12 member 1 antikoerper, solute carrier family 12, member 1 antikoerper, si:ch211-220f12.1 antikoerper, SLC12A1 antikoerper, Slc12a1 antikoerper

Hintergrund:

Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

Aliases: BSC1 antibody, Bumetanide sensitive sodium 3 antibody, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody, Kidney specific Na K Cl symporter antibody, Kidney-specific Na-K-Cl symporter antibody, MGC48843 antibody, Na K 2Cl cotransporter antibody, NKCC2 antibody, potassiumchloride cotransporter 2 antibody, S12A1_HUMAN antibody, Slc12a1 antibody, sodium potassium chloride cotransporter 2 antibody, solute carrier family 12 (sodium/potassium/chloride transporters) antibody, Solute carrier family 12 member 1 antibody

UniProt: Q13621