SQSTM1 Antikörper (Sequestosome 1)

Details for Product anti-SQSTM1 Antibody No. ABIN6567156
Target
Reaktivität
Human
220
122
99
5
5
5
5
4
4
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
186
26
6
3
Klonalität
Polyklonal
Konjugat
Dieser SQSTM1 Antikörper ist unkonjugiert
13
11
8
8
8
8
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
166
75
62
54
38
33
18
15
13
12
8
4
2
2
1
Optionen
Immunogen Recombinant protein of human SQSTM1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung P62/SQSTM1 (SQSTM1 Antibody Abstract)
Hintergrund

Synonyms: A170,DMRV,EBI 3 associated protein of 60 kDa,EBI 3 associated protein p60,EBI3 associated protein of 60 kDa,EBI3 associated protein p60,EBI3-associated protein of 60 kDa,EBIAP,FTDALS3,MGC127197,ORCA,OSF-6,Osi,OSIL,Oxidative stress induced like,p60,p62,p62B,Paget disease of bone 3,PDB 3,PDB3,Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa,Phosphotyrosine independent ligand for the Lck SH2 domain p62,Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa,PKC-zeta-interacting protein,Protein kinase C-zeta-interacting protein,Sequestosome 1,Sequestosome-1,SQSTM 1,SQSTM,Sqstm1,STAP,STONE14,Ubiquitin binding protein p62,Ubiquitin-binding protein p62,ZIP 3,ZIP,ZIP3

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Molekulargewicht

Observed_MW: 62kDa

Calculated_MW: 38kDa/47kDa

Gen-ID 8878
UniProt Q13501
Pathways NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:20 - 1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Sequestosome 1 (SQSTM1) antibody (ABIN6567156) Immunohistochemistry of paraffin-embedded human esophagus using SQSTM1 antibody.
Image no. 2 for anti-Sequestosome 1 (SQSTM1) antibody (ABIN6567156) Immunoprecipitation analysis of 100ug extracts of HepG2 cells using 3ug SQSTM1 antibody.
Image no. 3 for anti-Sequestosome 1 (SQSTM1) antibody (ABIN6567156) Western blot analysis of extracts of various cell lines, using SQSTM1 antibody.