Synonyms: Aryl hydrocarbon hydroxylase,CP37,CP3A7,CYP3A7,CYPIIIA7,Cytochrome P450 3A7,Cytochrome P450,family 3,subfamily A,polypeptide 7,Cytochrome P450,subfamily IIIA,polypeptide 7,Cytochrome P450-HFLA,Flavoprotein linked monooxygenase,Microsomal monooxygenase,P 450(HFL33),P 450111A7,P450 HFLA,Xenobiotic monooxygenase
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540.