CYP3A7 Antikörper (Center)

Produktnummer ABIN2855738

Produktdetails anti-CYP3A7 Antikörper

Target: CYP3A7 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP3A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Affe

Kreuzreaktivität (Details): Monkey (93 %)

Produktmerkmale: Rabbit Polyclonal antibody to CYP3A7 (cytochrome P450, family 3, subfamily A, polypeptide 7)
CYP3A7 antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP3A7. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: A549 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CYP3A7

Target: CYP3A7 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))

Andere Bezeichnung: CYP3A7 (CYP3A7 Produkte)

Synonyme: CP37 antikoerper, CYPIIIA7 antikoerper, P450-HFLA antikoerper, cytochrome P450, family 3, subfamily A, polypeptide 7 antikoerper, cytochrome P450 family 3 subfamily A member 7 antikoerper, CYP3A7 antikoerper

Hintergrund: This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.

Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane

Molekulargewicht: 58 kDa

Gen-ID: 1551

Pathways: Steroid Hormone Biosynthesis