Neurofilament Antikörper

Details zu Produkt Nr. ABIN6566538
Target
Reaktivität
Human, Maus, Ratte
41
34
31
23
23
3
1
1
Wirt
Kaninchen
36
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
28
23
16
13
11
9
3
2
1
1
Optionen
Immunogen Recombinant Protein of human NEFL
Isotyp IgG
Reinigung Affinity purification
Target
Hintergrund

Synonyms: 68 kDa neurofilament protein,68  kDa neurofilament protein,CMT1F,CMT2E,FLJ53642,Light molecular weight neurofilament protein,NEFL,Neurofilament light,Neurofilament light polypeptide 68  kDa,Neurofilament light polypeptide,Neurofilament protein,light chain,Neurofilament subunit NF L,Neurofilament triplet L protein,NF-L,NF68,NFL,NFL

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Molekulargewicht

Observed_MW: 82kDa

Calculated_MW: 61kDa

Gen-ID 4747
UniProt P07196
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Neurofilament antibody (ABIN6566538) Western blot analysis of extracts of MCF-7 cells, using NEFL antibody.
Image no. 2 for anti-Neurofilament antibody (ABIN6566538) Immunohistochemistry of paraffin-embedded rat kidney using NEFL antibody.
Image no. 3 for anti-Neurofilament antibody (ABIN6566538) Immunohistochemistry of paraffin-embedded rat brain using NEFL antibody.
Image no. 4 for anti-Neurofilament antibody (ABIN6566538) Immunofluorescence analysis of HeLa cells using NEFL antibody.