FASL Antikörper

Produktnummer ABIN6566520

Dieses Anti-FASL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FASL in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für FASL Antikörper (ABIN6566520)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FASL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FASL Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human FASLG

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Andere Bezeichnung: FASLG

Hintergrund:

Synonyms: ALPS1B,Apoptosis (APO 1) antigen ligand 1,Apoptosis antigen ligand 1,Apoptosis antigen ligand,APT1LG1,APTL,CD178,CD178 antigen,CD95 ligand,CD95-L,CD95L,CD95L protein,Fas antigen ligand,Fas L,Fas ligand (TNF superfamily member 6),Fas ligand,FASL,Fasl Fas ligand (TNF superfamily member 6),FASLG,Generalized lymphoproliferative disease,Gld,soluble form,TNFL6,TNFSF6,Tumor necrosis factor (ligand) superfamily member 6,Tumor necrosis factor ligand superfamily member 6

Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Molekulargewicht:

Observed_MW: 45kDa

Calculated_MW: 14kDa/31kDa

Gen-ID: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity