TRF1 Antikörper (Telomeric Repeat Binding Factor (NIMA-Interacting) 1)

Details for Product anti-TERF1 Antibody No. ABIN6566478
Target
Reaktivität
Human, Maus
79
29
19
1
1
1
1
1
1
Wirt
Kaninchen
64
10
8
Klonalität
Polyklonal
Konjugat
Dieser TRF1 Antikörper ist unkonjugiert
8
6
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
59
37
18
13
8
8
6
3
2
2
2
1
Optionen
Immunogen Recombinant protein of human TERF1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TERF1 (TERF1 Antibody Abstract)
Hintergrund

Synonyms: hTRF1 AS,NIMA interacting protein 2,NIMA-interacting protein 2,PIN 2,PIN2,t TRF1,Telomeric protein Pin2,Telomeric protein Pin2/TRF1,Telomeric repeat binding factor (NIMA interacting) 1,Telomeric repeat binding factor 1,Telomeric repeat binding protein 1,Telomeric repeat-binding factor 1,TERF 1,Terf1,TERF1,TRBF 1,TRBF1,TRF 1,TRF,TTAGGG repeat binding factor 1,TTAGGG repeat-binding factor 1

Background: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Molekulargewicht

Observed_MW: 62kDa

Calculated_MW: 48kDa/50kDa

Gen-ID 7013
UniProt P54274
Pathways Zellzyklus, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1) antibody (ABIN6566478) Western blot analysis of extracts of mouse eye, using TERF1 antibody.
Image no. 2 for anti-Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1) antibody (ABIN6566478) Immunohistochemistry of paraffin-embedded human gastric cancer using TERF1 antibody.