Factor XI Antikörper (AA 281-307)

Produktnummer ABIN655515

Dieses Anti-Factor XI-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Factor XI in WB und IHC (p). Geeignet für Human.

Kurzübersicht für Factor XI Antikörper (AA 281-307) (ABIN655515)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor XI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB19294

Produktdetails anti-Factor XI Antikörper

Bindungsspezifität: AA 281-307

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This F11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the Central region of human F11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Andere Bezeichnung: F11

Hintergrund: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].

Molekulargewicht: 70109

Gen-ID: 2160

NCBI Accession: NP_000119

UniProt: P03951