UNC13B Antikörper (AA 1062-1091)

Produktnummer ABIN2842552

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UNC13B in WB und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für UNC13B Antikörper (AA 1062-1091) (ABIN2842552)

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB22476

Produktdetails anti-UNC13B Antikörper

Bindungsspezifität: AA 1062-1091

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-UNC13B Antikörper (ABIN2842552)

Kasmapour, Gronow, Bleck, Hong, Gutierrez: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, (2012) (PubMed).

Details zu UNC13B

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Andere Bezeichnung: UNC13B

Hintergrund: UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

Molekulargewicht: 180679

Gen-ID: 10497

NCBI Accession: NP_006368

UniProt: O14795

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis