CTPS2 Antikörper (N-Term)

Produktnummer ABIN652725

Dieses Anti-CTPS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CTPS2 in WB und FACS. Geeignet für Human.

Kurzübersicht für CTPS2 Antikörper (N-Term) (ABIN652725)

Target: CTPS2 (CTP Synthase II (CTPS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB23574

Produktdetails anti-CTPS2 Antikörper

Bindungsspezifität: AA 77-105, N-Term

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human CTPS2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTPS2

Hintergrund: CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.

Molekulargewicht: 65678

Gen-ID: 56474

NCBI Accession: NP_001137474, NP_062831, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process