CTPS2 Antikörper (C-Term)

Produktnummer ABIN656954

Produktdetails anti-CTPS2 Antikörper

Target: CTPS2 (CTP Synthase II (CTPS2))

Bindungsspezifität: AA 450-479, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.

Klon: RB32822

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CTPS2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTPS2 (CTPS2 Produkte)

Synonyme: A830031M15Rik antikoerper, AI326475 antikoerper, Ctpsh antikoerper, CTP synthase 2 L homeolog antikoerper, CTP synthase 2 antikoerper, cytidine 5'-triphosphate synthase 2 antikoerper, ctps2.L antikoerper, CTPS2 antikoerper, ctps2 antikoerper, Ctps2 antikoerper

Hintergrund: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

Molekulargewicht: 65678

Gen-ID: 56474

NCBI Accession: NP_001137474, NP_062831, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process