CTPS2 Antikörper (C-Term)

Produktnummer ABIN951729

Produktdetails anti-CTPS2 Antikörper

Target: CTPS2 (CTP Synthase II (CTPS2))

Bindungsspezifität: AA 449-479, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CTPS2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 449-479 amino acids from the C-terminal region of human CTPS2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTP Synthase 2 (CTPS2 Produkte)

Synonyme: A830031M15Rik antikoerper, AI326475 antikoerper, Ctpsh antikoerper, CTP synthase 2 L homeolog antikoerper, CTP synthase 2 antikoerper, cytidine 5'-triphosphate synthase 2 antikoerper, ctps2.L antikoerper, CTPS2 antikoerper, ctps2 antikoerper, Ctps2 antikoerper

Hintergrund: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.Synonyms: CTP synthetase 2, CTPS2, UTP-ammonia ligase 2

Molekulargewicht: 65678 Da

Gen-ID: 56474

NCBI Accession: NP_001137474

Pathways: Ribonucleoside Biosynthetic Process