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FAK Antikörper (C-Term)

Dieses Anti-FAK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FAK in WB, IF, FACS und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN652554

Kurzübersicht für FAK Antikörper (C-Term) (ABIN652554)

Target

Alle FAK (PTK2) Antikörper anzeigen
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reaktivität

  • 344
  • 282
  • 214
  • 22
  • 21
  • 17
  • 16
  • 12
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 345
  • 28
  • 3
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 332
  • 48
Polyklonal

Konjugat

  • 175
  • 17
  • 16
  • 12
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 1
  • 1
Dieser FAK Antikörper ist unkonjugiert

Applikation

  • 308
  • 133
  • 133
  • 120
  • 110
  • 75
  • 67
  • 45
  • 41
  • 34
  • 31
  • 5
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB20776
  • Bindungsspezifität

    • 43
    • 36
    • 31
    • 28
    • 24
    • 22
    • 22
    • 21
    • 16
    • 16
    • 12
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 821-848, C-Term

    Homologie

    M, Rat

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-848 amino acids from the C-terminal region of human PTK2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Ma, He, Zhang, Fei, Niu, Wang, Ding, Xu, Chen, Zhu: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).

  • Target

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    Andere Bezeichnung

    PTK2

    Hintergrund

    PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

    Molekulargewicht

    119233

    Gen-ID

    5747

    NCBI Accession

    NP_001186578, NP_722560

    UniProt

    Q05397

    Pathways

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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