MUC20 Antikörper (N-Term)

Produktnummer ABIN652399

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MUC20 in WB und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für MUC20 Antikörper (N-Term) (ABIN652399)

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: RB12372

Produktdetails anti-MUC20 Antikörper

Bindungsspezifität: AA 61-90, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human MUC20.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MUC20 Antikörper (ABIN652399)

Wieben, Aleff, Eckloff, Atkinson, Baheti, Middha, Brown, Patel, Kocher, Baratz: "Comprehensive assessment of genetic variants within TCF4 in Fuchs' endothelial corneal dystrophy." in: Investigative ophthalmology & visual science, Vol. 55, Issue 9, pp. 6101-7, (2014) (PubMed).

Woodward, Argüeso: "Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6132-8, (2014) (PubMed).

Details zu MUC20

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Andere Bezeichnung: MUC20

Hintergrund: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 71982

Gen-ID: 200958

UniProt: Q8N307