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MUC20 Antikörper (C-Term)

MUC20 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB13033 unconjugated
Produktnummer ABIN652400
  • Target Alle MUC20 Antikörper anzeigen
    MUC20 (Mucin 20, Cell Surface Associated (MUC20))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 654-684, C-Term
    Reaktivität
    • 46
    • 11
    • 3
    Human
    Wirt
    • 46
    • 2
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 18
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MUC20 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 32
    • 26
    • 16
    • 12
    • 11
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20.
    Klon
    RB13033
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. IHC-P-Leica: 1:500. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Uchino, Woodward, Argüeso: "Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells." in: Experimental eye research, Vol. 153, pp. 1-7, (2017) (PubMed).

    Ohmori, Fujii, Kadochi, Mori, Nishiguchi, Fujiwara, Kishi, Sasaki, Kuniyasu: "Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 84, Issue 3, pp. 144-151, (2017) (PubMed).

    Woodward, Argüeso: "Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6132-8, (2014) (PubMed).

  • Target
    MUC20 (Mucin 20, Cell Surface Associated (MUC20))
    Andere Bezeichnung
    MUC20 (MUC20 Produkte)
    Synonyme
    BC026367 antikoerper, MUC-20 antikoerper, mucin-20 antikoerper, mucin 20 antikoerper, mucin 20, cell surface associated antikoerper, LOC750119 antikoerper, Muc20 antikoerper, MUC20 antikoerper
    Hintergrund
    This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    71982
    Gen-ID
    200958
    UniProt
    Q8N307
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