BAK1 Antikörper

Produktnummer ABIN645850

Dieser Ziege not_set Antikörper detektiert spezifisch BAK1 . Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für BAK1 Antikörper (ABIN645850)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reaktivität: Maus, Ratte

Wirt: Ziege

Konjugat: Dieser BAK1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-BAK1 Antikörper

Spezifität: The goat Anti-BAK1 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Kreuzreaktivität: Maus, Ratte (Rattus)

Produktmerkmale: Goat Anti-BAK1

Immunogen: Peptide with sequence C-ASGQGPGPPRQE, from the N Terminus of the protein sequence according to NP_001179, was used as immunogen.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Lagerung: -20 °C

Details zu BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Andere Bezeichnung: BAK1

Hintergrund: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

NCBI Accession: NP_001179

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response