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HLA-ABC Antikörper

Dieses Anti-HLA-ABC-Antikörper ist ein Ratte -Antikörper zur Detektion von HLA-ABC in FACS, IP und IHC (fro). Geeignet für Human.
Produktnummer ABIN642915

Kurzübersicht für HLA-ABC Antikörper (ABIN642915)

Target

Alle HLA-ABC Antikörper anzeigen
HLA-ABC

Reaktivität

  • 71
  • 28
  • 21
  • 19
  • 17
  • 13
  • 13
  • 12
  • 12
  • 11
  • 7
  • 7
  • 6
  • 6
  • 2
  • 1
Human

Wirt

  • 59
  • 10
  • 3
Ratte

Konjugat

  • 31
  • 8
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HLA-ABC Antikörper ist unkonjugiert

Applikation

  • 55
  • 18
  • 16
  • 14
  • 10
  • 10
  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Spezifität

    The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. DS-MB-01537 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. Recent studies have shown that this antibody may be able to induce apoptosis in activated but not resting T cells (1).

    Produktmerkmale

    Rat Anti-Human HLA ABC

    Aufreinigung

    Purified

    Immunogen

    PhA activated human peripheral blood lymphocytes.

    Isotyp

    IgG2b
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    IgG concentration 1.0 mg/ml

    Buffer

    Phosphate buffered saline

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C
  • Target

    HLA-ABC

    Andere Bezeichnung

    HLA ABC

    Hintergrund

    This antibody does not cross reacts with Fab or F(ab')2 of IgG. Some cross reaction with IgG of other species such as horse and sheep was observed. No cross reaction with human IgA, IgE or IgM.

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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