TLR7 Antikörper

Produktnummer ABIN639907

Dieser Maus Monoklonal Antikörper detektiert spezifisch TLR7 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TLR7 Antikörper (ABIN639907)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TLR7 Antikörper

Verwendungszweck: Mouse Anti-Human TLR7

Spezifität: DS-MB-03427 specifically recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein which belongs to the toll-like receptor (TLR) family, and is predominantly expressed in the spleen, lung and placenta. TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules.

Aufreinigung: Purified

Immunogen: Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA (dilution: 1/1000, 1/2000), Western Blotting

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Andere Bezeichnung: TLR7

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades