Der Kaninchen Polyklonal Anti-CD22 Antikörper wurde für WB, ELISA und Inhibition validiert. Er ist geeignet, CD22 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
CD22
Reaktivität: Human
FACS, WB, ELISA, IF, IP
Wirt: Kaninchen
Monoclonal
DM13
unconjugated
Applikationshinweise
Optimal conditions should be determined byt he investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Konzentration
Lot specific
Buffer
Lyophilized from PBS, pH 7.2.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
Lennon, Cao, Hall, Vickers, Barker: "The red blood cell as a novel regulator of human B-cell activation." in: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).
Target
CD22
(CD22 Molecule (CD22))
Andere Bezeichnung
CD22
Hintergrund
CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand.