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CD40 Ligand Antikörper

CD40LG Reaktivität: Human WB, ELISA, Inhibition Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN636590
  • Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen
    CD40 Ligand (CD40LG)
    Reaktivität
    • 156
    • 82
    • 34
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 93
    • 76
    • 25
    • 12
    • 10
    • 2
    Ziege
    Klonalität
    • 127
    • 86
    • 4
    Polyklonal
    Konjugat
    • 110
    • 23
    • 21
    • 14
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD40 Ligand Antikörper ist unkonjugiert
    Applikation
    • 120
    • 100
    • 57
    • 49
    • 40
    • 29
    • 22
    • 18
    • 16
    • 13
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    Aufreinigung
    Purified
    Immunogen
    CD40 L antibody was raised in goat using highly pure recombinant human sCD40 as the immunogen.
    Top Product
    Discover our top product CD40LG Primärantikörper
  • Applikationshinweise
    Optimal conditions should be determined byt he investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized from PBS, pH 7.2.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Target
    CD40 Ligand (CD40LG)
    Andere Bezeichnung
    CD40L (CD40LG Produkte)
    Hintergrund
    CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.
    Molekulargewicht
    16.3 kDa (predicted detection band MW)
    Pathways
    NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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