Presenilin 2 Antikörper
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- Target Alle Presenilin 2 (PSEN2) Antikörper anzeigen
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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Reaktivität
- Säugetier
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Presenilin 2 Antikörper ist unkonjugiert
- Applikation
- Bitte anfragen
- Aufreinigung
- Purified
- Top Product
- Discover our top product PSEN2 Primärantikörper
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- Applikationshinweise
- Optimal conditions should be determined byt he investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- Lot specific
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- Andere Bezeichnung
- Presenilin 2 (PSEN2 Produkte)
- Hintergrund
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.
- Pathways
- Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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