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SMPD3 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMPD3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN635767

Kurzübersicht für SMPD3 Antikörper (ABIN635767)

Target

Alle SMPD3 Antikörper anzeigen
SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Reaktivität

  • 25
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 24
  • 2
  • 1
Kaninchen

Klonalität

  • 27
Polyklonal

Konjugat

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
Dieser SMPD3 Antikörper ist unkonjugiert

Applikation

  • 20
  • 14
  • 5
  • 4
  • 2
Western Blotting (WB)
  • Aufreinigung

    Affinity purified

    Immunogen

    SMPD3 antibody was raised using a synthetic peptide corresponding to a region with amino acids RPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLV
  • Applikationshinweise

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    Kommentare

    SMPD3 Blocking Peptide, (ABIN5616306), is also available for use as a blocking control in assays to test for specificity of this SMPD3 antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SMPD3 antibody in PBS

    Konzentration

    Lot specific

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target

    SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

    Andere Bezeichnung

    SMPD3

    Hintergrund

    SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

    Molekulargewicht

    71 kDa (MW of target protein)

    Pathways

    Hormone Transport
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