SMPD3 Antikörper
Kurzübersicht für SMPD3 Antikörper (ABIN635767)
Target
Alle SMPD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purified
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Immunogen
- SMPD3 antibody was raised using a synthetic peptide corresponding to a region with amino acids RPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLV
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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SMPD3 Blocking Peptide, (ABIN5616306), is also available for use as a blocking control in assays to test for specificity of this SMPD3 antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SMPD3 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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Andere Bezeichnung
- SMPD3
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Hintergrund
- SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
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Molekulargewicht
- 71 kDa (MW of target protein)
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Pathways
- Hormone Transport
Target
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