KCNN3 Antikörper (C-Term)

Produktnummer ABIN633755

Produktdetails anti-KCNN3 Antikörper

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: KCNN3 antibody was raised against the C terminal of KCNN3

Aufreinigung: Affinity purified

Immunogen: KCNN3 antibody was raised using the C terminal of KCNN3 corresponding to a region with amino acids ITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSA

Anwendungsinformationen

Applikationshinweise: WB: 2 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

KCNN3 Blocking Peptide, catalog no. 33R-4172, is also available for use as a blocking control in assays to test for specificity of this KCNN3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNN3 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu KCNN3

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Andere Bezeichnung: KCNN3 (KCNN3 Produkte)

Synonyme: KCa2.3 antikoerper, SK3 antikoerper, SKCA3 antikoerper, hSK3 antikoerper, potassium calcium-activated channel subfamily N member 3 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antikoerper, Kcnn3 antikoerper, KCNN3 antikoerper

Hintergrund: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

Molekulargewicht: 81 kDa (MW of target protein)