KCNN3 Antikörper (C-Term)

Produktnummer ABIN2776146

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KCNN3 in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für KCNN3 Antikörper (C-Term) (ABIN2776146)

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNN3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-KCNN3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: KCNN3 Antibody - C-terminal region

Sequenz: ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNN3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111908

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNN3

Target: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Andere Bezeichnung: KCNN3

Hintergrund:

Background Information: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

Gene Name: Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Alternative Symbols: SK3, ZLS3, hSK3, SKCA3, KCa2.3

Protein Name: Small conductance calcium-activated potassium channel protein 3

Molekulargewicht: 81kDa

Gen-ID: 3782

NCBI Accession: NP_002240

UniProt: Q9UGI6