MLF1 Antikörper (N-Term)
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- Target Alle MLF1 Antikörper anzeigen
- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MLF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- MLF1 antibody was raised against the N terminal of MLF1
- Aufreinigung
- Affinity purified
- Immunogen
- MLF1 antibody was raised using the N terminal of MLF1 corresponding to a region with amino acids GRDLLSISDGRGRAHNRRGHNDGEDSLTHTDVSSFQTMDQMVSNMRNYMQ
- Top Product
- Discover our top product MLF1 Primärantikörper
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- Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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MLF1 Blocking Peptide, catalog no. 33R-3521, is also available for use as a blocking control in assays to test for specificity of this MLF1 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MLF1 antibody in PBS
- Konzentration
- Lot specific
- Buffer
- PBS
- Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
- Andere Bezeichnung
- MLF1 (MLF1 Produkte)
- Synonyme
- MLF1 antikoerper, HLS7 antikoerper, myeloid leukemia factor 1 antikoerper, myeloid leukemia factor 1 L homeolog antikoerper, MLF1 antikoerper, mlf1.L antikoerper, mlf1 antikoerper, Mlf1 antikoerper
- Hintergrund
- MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
- Molekulargewicht
- 29 kDa (MW of target protein)
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