Butyrylcholinesterase Antikörper (N-Term)
Kurzübersicht für Butyrylcholinesterase Antikörper (N-Term) (ABIN630462)
Target
Alle Butyrylcholinesterase (BCHE) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- BCHE antibody was raised against the N terminal of BCHE
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Aufreinigung
- Purified
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Immunogen
- BCHE antibody was raised using the N terminal of BCHE corresponding to a region with amino acids SSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ
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Applikationshinweise
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WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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BCHE Blocking Peptide, (ABIN5612293), is also available for use as a blocking control in assays to test for specificity of this BCHE antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BCHE antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Butyrylcholinesterase (BCHE)
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Andere Bezeichnung
- BCHE
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Hintergrund
- Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
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Molekulargewicht
- 68 kDa (MW of target protein)
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Pathways
- Peptide Hormone Metabolism
Target
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