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Butyrylcholinesterase Antikörper (N-Term)

BCHE Reaktivität: Human, Maus, Hund, Ratte, Schaf, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781762
  • Target Alle Butyrylcholinesterase (BCHE) Antikörper anzeigen
    Butyrylcholinesterase (BCHE)
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Hund, Ratte, Schaf, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Kaninchen
    Wirt
    • 53
    • 20
    Kaninchen
    Klonalität
    • 53
    • 20
    Polyklonal
    Konjugat
    • 27
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Butyrylcholinesterase Antikörper ist unkonjugiert
    Applikation
    • 56
    • 26
    • 22
    • 13
    • 11
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    SSLHVYDGKF LARVERVIVV SMNYRVGALG FLALPGNPEA PGNMGLFDQQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against BCHE. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human BCHE
    Top Product
    Discover our top product BCHE Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 602 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mizukami, Akatsu, Abrahamson, Mi, Ikonomovic: "Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 2, pp. 135-45, (2016) (PubMed).

  • Target
    Butyrylcholinesterase (BCHE)
    Andere Bezeichnung
    BCHE (BCHE Produkte)
    Synonyme
    che antikoerper, che1 antikoerper, bche antikoerper, cholinesterase antikoerper, CHE1 antikoerper, CHE2 antikoerper, E1 antikoerper, C730038G20Rik antikoerper, butyrylcholinesterase L homeolog antikoerper, butyrylcholinesterase antikoerper, bche.L antikoerper, bche antikoerper, BCHE antikoerper, Bche antikoerper
    Hintergrund
    Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
    Alias Symbols: CHE1, E1
    Protein Interaction Partner: COLQ, BCHE,
    Protein Size: 602
    Molekulargewicht
    68 kDa
    Gen-ID
    590
    NCBI Accession
    NM_000055, NP_000046
    UniProt
    P06276
    Pathways
    Peptide Hormone Metabolism
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