MUSK Antikörper
Kurzübersicht für MUSK Antikörper (ABIN6297871)
Target
Alle MUSK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit Anti-MUSK Antibody
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Immunogen
- This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Andere Bezeichnung
- MUSK
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Hintergrund
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Target Description: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Gene Symbol: MUSK
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Gen-ID
- 4593
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UniProt
- O15146
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Pathways
- RTK Signalweg, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
Target
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