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EGFR Antikörper

EGFR Reaktivität: Human IF, FACS, IHC (fp) Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297747
  • Target Alle EGFR Antikörper anzeigen
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Reaktivität
    • 762
    • 299
    • 287
    • 25
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    • 24
    • 20
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    Human
    Wirt
    • 581
    • 178
    • 14
    • 13
    • 5
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 543
    • 249
    • 2
    Monoklonal
    Konjugat
    • 416
    • 58
    • 29
    • 22
    • 20
    • 18
    • 18
    • 17
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    • 16
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGFR Antikörper ist unkonjugiert
    Applikation
    • 538
    • 252
    • 154
    • 151
    • 128
    • 102
    • 99
    • 93
    • 82
    • 46
    • 37
    • 34
    • 34
    • 19
    • 11
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    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Mouse anti-Human EGFR Antibody [Sodium Azide Free]
    Spezifität
    Cell surface
    Aufreinigung
    The immunizing protein for this antibody was recombinant human EGFR.
    Immunogen
    The immunizing protein for this antibody was recombinant human EGFR.
    Top Product
    Discover our top product EGFR Primärantikörper
  • Applikationshinweise
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    FACS: 0.5-1 μg/million cells in 0.1ml
    IF: 1-2 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Andere Bezeichnung
    Epidermal growth factor receptor (EGFR Produkte)
    Hintergrund

    Target Description: This antibody recognizes a protein of 170 kDa, identified as EGFR.  < a href=../search_result.php?search_txt=egfr>EGFR  is type I receptor tyrosine kinase with sequence homology to  < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or  < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF),  < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a  (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head/neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

    Gene Symbol: EGFR///ERBB///ERBB1///HER1

    Gen-ID
    1956
    UniProt
    P00533
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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