EGFR Antikörper
Kurzübersicht für EGFR Antikörper (ABIN6297747)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Mouse anti-Human EGFR Antibody [Sodium Azide Free]
-
Spezifität
- Cell surface
-
Aufreinigung
- The immunizing protein for this antibody was recombinant human EGFR.
-
Immunogen
- The immunizing protein for this antibody was recombinant human EGFR.
-
-
-
-
Applikationshinweise
-
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
FACS: 0.5-1 μg/million cells in 0.1ml
IF: 1-2 μg/mL -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
-
Konservierungsmittel
- Azide free
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
Andere Bezeichnung
- Epidermal growth factor receptor
-
Hintergrund
-
Target Description: This antibody recognizes a protein of 170 kDa, identified as EGFR. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head/neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Gene Symbol: EGFR///ERBB///ERBB1///HER1
-
Gen-ID
- 1956
-
UniProt
- P00533
-
Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
-