Cytokeratin 18 Antikörper

Produktnummer ABIN6297738

Dieses Anti-Cytokeratin 18-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cytokeratin 18 in WB, IHC, IF und FACS. Geeignet für Human.

Kurzübersicht für Cytokeratin 18 Antikörper (ABIN6297738)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Cytokeratin 18 Antikörper

Verwendungszweck: Mouse anti-Human Cytokeratin 18 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.

Immunogen: The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: Keratin, type I cytoskeletal 18

Hintergrund:

Target Description: This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Gene Symbol: KRT18///CYK18///PIG46

Gen-ID: 3875

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose