CD44 Antikörper
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- Target Alle CD44 Antikörper anzeigen
- CD44
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Reaktivität
- Human, Pavian, Green Monkey
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD44 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Verwendungszweck
- Mouse anti-Human/Baboon/Green Monkey HCAM Antibody CD44 [IHC only]
- Spezifität
- Cell surface
- Aufreinigung
- Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.
- Top Product
- Discover our top product CD44 Primärantikörper
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- Applikationshinweise
- Prediluted format : incubate for 30 min at RT (2)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD44
- Andere Bezeichnung
- CD44 antigen (CD44 Produkte)
- Hintergrund
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Target Description: This antibody recognizes a cell surface glycoprotein of 80-95 kDa, called CD44, or HCAM, on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44-s). Higher molecular weight isoforms are described in epithelial cells (CD44-v), which are believed to function in intercellular adhesion and stromal binding. HCAM antibody immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
Gene Symbol: CD44///LHR///MDU2///MDU3///MIC4
- Gen-ID
- 960
- UniProt
- P16070
- Pathways
- Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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