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CD53 Antikörper

CD53 Reaktivität: Human FACS, IF, Func Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297690
  • Target Alle CD53 Antikörper anzeigen
    CD53
    Reaktivität
    • 66
    • 5
    • 2
    Human
    Wirt
    • 43
    • 23
    • 2
    Maus
    Klonalität
    • 44
    • 22
    • 2
    Monoklonal
    Konjugat
    • 26
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD53 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 29
    • 25
    • 13
    • 13
    • 11
    • 9
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Verwendungszweck
    Mouse anti-Human CD53 Antibody [Sodium Azide Free]
    Spezifität
    Cell surface
    Aufreinigung
    Stimulated human leukocytes were used as the immunogen for the CD53 antibody.
    Immunogen
    Stimulated human leukocytes were used as the immunogen for the CD53 antibody.
    Top Product
    Discover our top product CD53 Primärantikörper
  • Applikationshinweise
    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    CD53
    Andere Bezeichnung
    Leukocyte surface antigen CD53 (CD53 Produkte)
    Synonyme
    AI323659 antikoerper, Ox-44 antikoerper, Tspan25 antikoerper, MOX44 antikoerper, TSPAN25 antikoerper, OX44 antikoerper, CD53 antigen antikoerper, CD53 molecule antikoerper, Cd53 molecule antikoerper, Cd53 antikoerper, CD53 antikoerper
    Hintergrund

    Target Description: Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI, Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This mAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).

    Gene Symbol: CD53///MOX44///TSPAN25

    Gen-ID
    963
    UniProt
    P19397
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