CD53 Antikörper
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- Target Alle CD53 Antikörper anzeigen
- CD53
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD53 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Verwendungszweck
- Mouse anti-Human CD53 Antibody [Sodium Azide Free]
- Spezifität
- Cell surface
- Aufreinigung
- Stimulated human leukocytes were used as the immunogen for the CD53 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD53 antibody.
- Top Product
- Discover our top product CD53 Primärantikörper
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- Applikationshinweise
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Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD53
- Andere Bezeichnung
- Leukocyte surface antigen CD53 (CD53 Produkte)
- Synonyme
- AI323659 antikoerper, Ox-44 antikoerper, Tspan25 antikoerper, MOX44 antikoerper, TSPAN25 antikoerper, OX44 antikoerper, CD53 antigen antikoerper, CD53 molecule antikoerper, Cd53 molecule antikoerper, Cd53 antikoerper, CD53 antikoerper
- Hintergrund
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Target Description: Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI, Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This mAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Gene Symbol: CD53///MOX44///TSPAN25
- Gen-ID
- 963
- UniProt
- P19397
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