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CD46 Antikörper

CD46 Reaktivität: Human, Pavian FACS, IF Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297689
  • Target Alle CD46 Antikörper anzeigen
    CD46
    Reaktivität
    • 112
    • 38
    • 20
    • 10
    • 9
    • 1
    Human, Pavian
    Wirt
    • 83
    • 49
    • 2
    Maus
    Klonalität
    • 72
    • 62
    Monoklonal
    Konjugat
    • 50
    • 17
    • 16
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD46 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 76
    • 41
    • 40
    • 33
    • 15
    • 14
    • 14
    • 13
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Verwendungszweck
    Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]
    Spezifität
    Cell surface
    Aufreinigung
    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
    Immunogen
    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
    Top Product
    Discover our top product CD46 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    CD46
    Andere Bezeichnung
    Membrane cofactor protein (CD46 Produkte)
    Synonyme
    AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
    Hintergrund

    Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

    Gene Symbol: CD46///MCP///MIC10

    Gen-ID
    4179
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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