Cadherin-16 Antikörper

Produktnummer ABIN6297278

Der Maus Monoklonal Anti-Cadherin-16-Antikörper wurde für IHC, IF und FACS validiert. Er ist geeignet, Cadherin-16 in Proben von Human, Maus, Ratte, Hund und Kaninchen zu detektieren.

Kurzübersicht für Cadherin-16 Antikörper (ABIN6297278)

Target: Cadherin-16 (CDH16)

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Cadherin-16 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Rabbit/Dog Cadherin 16 Antibody [Sodium Azide Free]

Spezifität: Cell surface with some cytoplasmic

Aufreinigung: Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.

Immunogen: Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: Cadherin-16

Hintergrund:

Target Description: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Gene Symbol: CDH16///UNQ695///PRO1340

Gen-ID: 1014

UniProt: O75309