PAX6 Antikörper

Produktnummer ABIN6297257

Der Maus-Monoklonal Anti-PAX6-Antikörper wurde für WB, IF und FACS validiert. Er ist geeignet zum Nachweis von PAX6 in Proben aus Human, Maus, Ratte und Huhn. }

Kurzübersicht für PAX6 Antikörper (ABIN6297257)

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-PAX6 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Chicken PAX6 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: Recombinant human PAX6 protein was used as the immunogen for this antibody.

Immunogen: Recombinant human PAX6 protein was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 0.5-1 μg/mL,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: Paired box protein Pax-6

Hintergrund:

Target Description: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters ' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

Gene Symbol: PAX6///AN2

Gen-ID: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis